Eicosatetraenoic acids substituted in any position by one or more hydroxy groups. They are important intermediates in a series of biosynthetic processes leading from arachidonic acid to a number of biologically active compounds such as prostaglandins, thromboxanes, and leukotrienes.

A colorless, syrupy, strongly acidic liquid that can form detergents with oleic acid.

An enzyme of the lyase class that catalyzes the cleavage of the bond between carbons 17 and 20 in 17-alpha hydroxyprogesterone to form delta 4-androstene-3,17-dione, an androgen. It also catalyzes the conversion of 17 alpha-hydroxypregnenolone to dehydroepiandrosterone. (from Dorland, 28th ed) EC 4.1.2.30.

Metabolite of serotonin and norepinephrine.

A heterogeneous group of inherited metabolic disorders marked by absent or dysfunctional PEROXISOMES. Peroxisomal enzymatic abnormalities may be single or multiple. Biosynthetic peroxisomal pathways are compromised, including the ability to synthesize ether lipids and to oxidize long-chain fatty acid precursors. Diseases in this category include ZELLWEGER SYNDROME; infantile Refsum disease; rhizomelic chondrodysplasia (CHONDRODYSPLASIA PUNCTATA, RHIZOMELIC); hyperpipecolic acidemia; neonatal adrenoleukodystrophy; and ADRENOLEUKODYSTROPHY (X-linked). Neurologic dysfunction is a prominent feature of most peroxisomal disorders.

Substances used to lower plasma cholesterol levels.

Agents which lower the blood glucose level.

Substances used to treat HYPERLIPIDEMIA.

Inorganic or organic derivatives of phosphinic acid, H2PO(OH). They include phosphinates and phosphinic acid esters.

Complete or severe loss of the subjective sense of taste, frequently accompanied by OLFACTION DISORDERS.