A zinc containing enzyme of the hydrolase class that catalyzes the removal of the N-terminal amino acid from most L-peptides, particularly those with N-terminal leucine residues but not those with N-terminal lysine or arginine residues. This occurs in tissue cell cytosol, with high activity in the duodenum, liver, and kidney. EC 3.4.11.1

A cytokine that activates neutrophils and attracts neutrophils and T-lymphocytes. It is released by several cell types including monocytes, macrophages, T-lymphocytes, fibroblasts, endothelial cells, and keratinocytes by an inflammatory stimulus. IL-8 is a member of the beta-thromboglobulin superfamily and structurally related to platelet factor 4.

Surface ligands, usually glycoproteins, that mediate cell-to-cell adhesion. Their functions include the assembly and interconnection of various vertebrate systems, as well as maintenance of tissue integration, wound healing, morphogenic movements, cellular migrations, and metastasis.

A potent and long acting analog of naturally occurring gonadotropin-releasing hormone (GONADORELIN). Its action is similar to gonadorelin, which regulates the synthesis and release of pituitary gonadotropins.

An acetic acid ester of CARNITINE that facilitates movement of acetyl CoA into the matrices of mammalian mitochondria during the oxidation of fatty acids.

A sugar acid derived from D-glucose in which both the aldehydic carbon atom and the carbon atom bearing the primary hydroxyl group are oxidized to carboxylic acid groups.

A narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence.

A narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence.

Keto acids that are derivatives of 4-oxopentanoic acids (levulinic acid).

A sugar acid derived from D-glucose in which both the aldehydic carbon atom and the carbon atom bearing the primary hydroxyl group are oxidized to carboxylic acid groups.