Acute Inflammatory Demyelinating Polyradiculoneuropathy Definition


Acute Inflammatory Demyelinating Polyradiculoneuropathy:

An acute inflammatory autoimmune neuritis caused by T cell- mediated cellular immune response directed towards peripheral myelin. Demyelination occurs in peripheral nerves and nerve roots. The process is often preceded by a viral or bacterial infection, surgery, immunization, lymphoma, or exposure to toxins. Common clinical manifestations include progressive weakness, loss of sensation, and loss of deep tendon reflexes. Weakness of respiratory muscles and autonomic dysfunction may occur. (From Adams et al., Principles of Neurology, 6th ed, pp1312-1314)

Synonym: aidp, acute inflammatory polyradiculoneuropathy, acute inflammatory polyneuropathy, acute autoimmune neuropathy, landry guillain barre syndrome, inflammatory polyneuropathy acute, guillaine barre syndrome, guillain barre syndrome, acute inflammatory polyradiculoneuropathies.