Acute Necrotizing Pancreatitis Definition

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Acute Necrotizing Pancreatitis:

Acute inflammation of the pancreas with areas of devitalized pancreatic and/or peripancreatic tissue. These necrotic areas may involve large areas of the pancreas or may be small. When a CT scan is performed with contrast media using a bolus technique, necrotic areas do not perfuse with media and are not enhanced. The lack of enhancement distinguishes necrotic tissue from the adjacent well-perfused viable pancreatic parenchyma. (From Liang et al., Pancreas: Biology, Pathobiology, & Disease, 2d ed, p597)