Terms Related to Bio-Breeding Inbred Rat

• Brattleboro Rats

  A mutant strain of Rattus norvegicus used in research on renal function and hypertension and as a disease model for diabetes insipidus.

• Inbred NOD Mouse

  A strain of non-obese diabetic mice developed in Japan that has been widely studied as a model for T-cell-dependent autoimmune insulin-dependent diabetes mellitus in which ...

• Experimental Diabetes Mellitus

  Diabetes mellitus induced experimentally by administration of various diabetogenic agents or by pancreatectomy.

• Inbred WKY Rat

  A strain of Rattus norvegicus used as a normotensive control for the spontaneous hypertensive rats (SHR).

• Inbred SHR Rat

  A strain of Rattus norvegicus with elevated blood pressure used as a model for studying hypertension and stroke.

• Inbred OLETF Rat

  An inbred strain of Long-Evans rats that develops hyperglycemia, hyperinsulinemia, and mild obesity, mostly in males, that resembles non-insulin-dependent diabetes mellitus in humans. It was ...

• Type I Diabetes Mellitus

  Diabetes mellitus characterized by insulin deficiency, sudden onset, severe hyperglycemia, rapid progression to ketoacidosis, and death unless treated with insulin. The disease may occur at ...