Medical Conditions Terminology in Category G

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gag-jun Fusion Proteins

Transforming protein coded by jun oncogenes (GENES, JUN). This is a gag-onc fusion protein of about 65 kD derived from avian sarcoma virus. v-jun lacks a negative regulatory domain that regulates transcription in c-jun.

Gagging

Clinical manifestation of the digestive system consisting of contraction of the muscle of the pharynx caused by stimulation of sensory receptors on the soft palate, by psychic stimuli, or systemically by drugs.

gag-fos-fox Fusion Proteins

Transforming proteins coded by fos oncogenes. These proteins have been found in the Finkel-Biskis-Jinkins (FBJ-MSV) and Finkel-Biskis-Reilly (FBR-MSV) murine sarcoma viruses which induce osteogenic sarcomas in mice. The FBJ-MSV v-fos gene encodes a p55 kD protein and the FBR-MSV v-fos gene encodes a p75 kD fusion protein.

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gag Viral Proteins

Proteins coded by the retroviral gag gene. The products are usually synthesized as protein precursors or POLYPROTEINS, which are then cleaved by viral proteases to yield the final products. Many of the final products are associated with the nucleoprotein core of the virion. gag is short for group-specific antigen.

gag Protein

Proteins coded by the retroviral gag gene. The products are usually synthesized as protein precursors or POLYPROTEINS, which are then cleaved by viral proteases to yield the final products. Many of the final products are associated with the nucleoprotein core of the virion. gag is short for group-specific antigen.

gag Polyprotein

Proteins coded by the retroviral gag gene. The products are usually synthesized as protein precursors or POLYPROTEINS, which are then cleaved by viral proteases to yield the final products. Many of the final products are associated with the nucleoprotein core of the virion. gag is short for group-specific antigen.

gag pol Protein

Polyprotein products of a fused portion of retroviral mRNA containing the gag and pol genes. The polyprotein is synthesized only five percent of the time since pol is out of frame with gag, and is generated by ribosomal frameshifting.

gag pol Fusion Proteins

Polyprotein products of a fused portion of retroviral mRNA containing the gag and pol genes. The polyprotein is synthesized only five percent of the time since pol is out of frame with gag, and is generated by ribosomal frameshifting.

gag pol Fused Protein

Polyprotein products of a fused portion of retroviral mRNA containing the gag and pol genes. The polyprotein is synthesized only five percent of the time since pol is out of frame with gag, and is generated by ribosomal frameshifting.

gag onc Fusion Proteins

General name for the translation products of a fusion mRNA consisting of a gag gene and a viral oncogene (v-onc). These products are thought to have the ability to transform cells.