A progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary CUSHING SYNDROME.

A phosphodiesterase inhibitor with antidepressant properties.

An eicosanoid, derived from the cyclooxygenase pathway of arachidonic acid metabolism. It is a stable and synthetic analog of EPOPROSTENOL, but with a longer half-life than the parent compound. Its actions are similar to prostacyclin. Iloprost produces vasodilation and inhibits platelet aggregation.

A semi-synthetic macrolide antibiotic structurally related to ERYTHROMYCIN. It has been used in the treatment of Mycobacterium avium intracellulare infections, toxoplasmosis, and cryptosporidiosis.

One of the SELECTIVE ESTROGEN RECEPTOR MODULATORS, it is agonist for bone tissue and cholesterol metabolism but antagonist in mammary and uterine tissues.

A potent second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. Unlike many traditional antihistamines, it does not cause drowsiness or anticholinergic side effects.

Zirconium. A rather rare metallic element, atomic number 40, atomic weight 91.22, symbol Zr. (From Dorland, 28th ed)

A class of protozoa consisting of animal-like flagellates. Its organisms are heterotrophic and have one-to-many flagella. This class includes one superorder, Parabasalidea, and six orders: Choanoflagellida, KINETOPLASTIDA, Proteromonadida, Retortamonadida, DIPLOMONADIDA, and Oxymonadida.

A genus of PSEUDOMONADACEAE occurring as rod-shaped cells embedded in a gelatinous matrix. It includes Z. filipendula.

The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)