HIV Encephalopathy Definition

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HIV Encephalopathy:

A neurologic condition associated with the ACQUIRED IMMUNONDEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefication, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)

Synonym: aids related dementia complex, aids encephalopathy, aids dementia complex, acquired-immune deficiency syndrome dementia complex, hiv dementia, hiv associated cognitive motor complex, hiv 1 cognitive and motor complex, hiv 1 associated cognitive motor complex.