Hyperalgesia Definition


Hyperalgesia: An increased sensation to painful stimuli that may follow damage to soft tissue containing NOCICEPTORS or injury to a peripheral nerve. Hyperalgesia can occur both at the site of tissue damage (primary hyperalgesia) and in the surrounding undamaged areas (secondary hyperalgesia). (Kandel et al., Principles of Neural Science, 3d ed, p386)

Synonym: thermal hyperalgesia, tactile hyperalgesia, secondary hyperalgesia, primary hyperalgesia, hyperalgesic sensation.