Immunoglobulin: Glycoproteins present in the blood (ANTIBODIES) and in other tissue. They are classified by structure and activity into five classes (IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M).

Synonym: immunoglobulin alterations, immunoglobulins, immune globulins.

Terms Related to Immunoglobulin

• epsilon Immunoglobulin

  Heavy chains found in the Fab and Fc fragments of IMMUNOGLOBULIN E and having a molecular weight of approximately 72 kD. They contain about 550 ...

• J Chain Immunoglobulins

  The immunoglobulin fragments found in the light chain fractions of secretory IMMUNOGLOBULIN A and polymeric IMMUNOGLOBULIN M in a ratio of one J chain per ...

• Helminth Antibodies

  Antibodies produced by human or animal cells following clinical or experimental exposure to parasitic helminth antigens. The IMMUNOGLOBULIN E class of immunoglobulins is usually formed ...

• epsilon Chain Immunoglobulins

  Heavy chains found in the Fab and Fc fragments of IMMUNOGLOBULIN E and having a molecular weight of approximately 72 kD. They contain about 550 ...

• Immunoglobulin D

  An immunoglobulin which accounts for less than 1% of plasma immunoglobulin. It is found on the membrane of many circulating B lymphocytes.

• Rheumatoid Factor

  Antibodies directed against antigenic determinants, i.e., Gm (gamma chain), in the Fc region of IMMUNOGLOBULIN G, found in the serum of about 80% of patients ...

• Polymeric Immunoglobulin Receptor

  Specialized Fc receptors (RECEPTORS, FC) for polymeric immunoglobulins, which mediate transcytosis of polymeric IMMUNOGLOBULIN A and IMMUNOGLOBULIN M into external secretions. They are found on ...

• gamma Immunoglobulin

  Heavy chains found in the Fab and Fc fragments of IMMUNOGLOBULIN G and having a molecular weight of approximately 51 kD. They contain about 450 ...

• Immunoglobulin A

  Represents 15-20% of the human serum immunoglobulins, mostly as the 4-chain polymer in humans or dimer in other mammals. Secretory IgA (IMMUNOGLOBULIN A, SECRETORY) ...

• Paraimmunoglobulinemia

  A group of related diseases characterized by an unbalanced or disproportionate proliferation of immunoglobulin-producing cells, usually from a single clone. These cells frequently secrete a ...