Terms Related to Linkage

• Linkage Mapping

  Any method used for determining the location of and relative distances between genes on a chromosome.

• Linkage Disequilibrium

  Nonrandom association of linked genes. This is the tendency of the alleles of two separate but already linked loci to be found together more frequently ...

• Genetic Epistasis

  A form of gene interaction whereby one gene interferes with the phenotypic expression of another nonallelic gene or genes. Genes whose expression is altered by ...

• nf 2 Genes

  Tumor suppressor genes located on the long arm of human chromosome 22. Mutation or loss of these genes causes NEUROFIBROMATOSIS 2.

• Recombination Activating Genes 1

  Genes involved in activating the enzyme VDJ recombinase. RAG-1 is located on chromosome 11 in humans (chromosome 2 in mice) and is expressed exclusively in ...

• Neurofibromatosis 2 Genes

  Tumor suppressor genes located on the long arm of human chromosome 22. Mutation or loss of these genes causes NEUROFIBROMATOSIS 2.

• RAG-1 Gene

  Genes involved in activating the enzyme VDJ recombinase. RAG-1 is located on chromosome 11 in humans (chromosome 2 in mice) and is expressed exclusively in ...