Terms Related to Multidrug Resistance Protein 1

• Multidrug Resistance Proteins

  A subfamily of transmembrane proteins from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS that are closely related in sequence to P-GLYCOPROTEIN. When overexpressed, they function as ...

• Multidrug Resistance-Associated Protein

  A sequence-related subfamily of ATP-BINDING CASSETTE TRANSPORTERS that actively transport organic substrates. Although considered organic anion transporters, a subset of proteins in this family have ...

• Multidrug Resistance Gene-1

  Genes responsible for multidrug resistance resulting from their overexpression in mammalian cells. Mammalian P-glycoproteins are encoded by small MDR gene familes. The human multidrug resistance ...

• Fungal Multidrug Resistance

  The ability of fungi to resist or to become tolerant to several structurally and functionally distinct drugs simultaneously. This resistance phenotype may be attributed to ...

• Rhodamine 123

  A fluorescent probe with low toxicity which is a potent substrate for P-glycoprotein and the bacterial multidrug efflux transporter. It is used to assess mitochondrial ...

• Antineoplastic Drug Resistance

  Resistance or diminished response of a neoplasm to an antineoplastic agent in humans, animals, or cell or tissue cultures.

• Multiple Drug Resistance

  Simultaneous resistance to several structurally and functionally distinct drugs.