Terms Related to Nonsense Mutation Suppressor Genes

• Genetic Suppression

  The restoration of the wild-type phenotype in an organism possessing a mutationally altered genotype. The effects of the mutation may be suppressed by a second ...

• nf 2 Genes

  Tumor suppressor genes located on the long arm of human chromosome 22. Mutation or loss of these genes causes NEUROFIBROMATOSIS 2.

• Translation Polarity

  Decrease in the synthesis of proteins specified by genes distal to the operator and to the site of a nonsense, frameshift, deletion or insertion mutation ...

• Neurofibromatosis 2 Genes

  Tumor suppressor genes located on the long arm of human chromosome 22. Mutation or loss of these genes causes NEUROFIBROMATOSIS 2.

• Neurofibromatosis 1 Genes

  Tumor suppressor genes located on the long arm of human chromosome 17 in the region 17q11.2. Mutation of these genes is thought to cause NEUROFIBROMATOSIS ...

• APC Genes

  Tumor suppressor genes located in the 5q21 region on the long arm of human chromosome 5. The mutation of these genes is associated with familial ...

• Onco-Suppressor Gene

  Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or ...