Nonsense Mutation Definition

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Nonsense Mutation: A codon that has been converted to the same sequence as a stop codon (CODON, TERMINATOR) by a nonsense mutation. It is different from a stop codon in that it occurs abnormally and causes premature termination of protein translation resulting in the production of truncated proteins which may be non-functional.

Synonym: unassigned codon, termination, premature codon, premature termination codon, premature stop codon, nonsense codon.