Terms Related to Ochronosis

• Alkaptonuria

  An inborn error of amino acid metabolism resulting from a defect in the enzyme homogentisate 1,2-dioxygenase and causing an accumulation of homogentisic acid in the ...

• Mucinosis

  Mucoid states characterized by the elevated deposition and accumulation of mucin (mucopolysaccharides) in dermal tissue. The fibroblasts are responsible for the production of acid mucopolysaccharides ...

• Tyrosine Phenol Lyase

  An enzyme that catalyzes the cleavage of tyrosine to phenol, pyruvate, and ammonia. It is a pyridoxal phosphate protein. The enzyme also forms pyruvate from ...

• Phenylalanine Ammonia-Lyase

  An enzyme that catalyzes the deamination of L-phenylalanine to form trans-cinnamate and ammonia. It may also act on L-tyrosine. Since the enzyme deprives neoplastic tissue ...

• Steatitis

  A disease of cats and mink characterized by a marked inflammation of adipose tissue and the deposition of "ceroid" pigment in the interstices of the ...

• Rheumatic Disease

  Disorders of connective tissue, especially the joints and related structures, characterized by inflammation, degeneration, or metabolic derangement.

• Connective Tissue Disease

  A heterogeneous group of disorders, some hereditary, others acquired, characterized by abnormal structure or function of one or more of the elements of connective tissue, ...