A group of related diseases characterized by an unbalanced or disproportionate proliferation of immunoglobulin-producing cells, usually from a single clone. These cells frequently secrete a structurally homogeneous immunoglobulin (M-component) and/or an abnormal immunoglobulin.
Abnormal immunoglobulins synthesized by atypical cells of the reticuloendothelial system. Paraproteins containing only light chains lead to Bence Jones paraproteinemia, while the presence of only ...
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