Pernicious Anemia: A megaloblastic anemia occurring in children but more commonly in later life, characterized by histamine-fast achlorhydria, in which the laboratory and clinical manifestations are based on malabsorption of vitamin B 12 due to a failure of the gastric mucosa to secrete adequate and potent intrinsic factor. (Dorland, 27th ed)

Synonym: addisons anemia, addison anemia.

Terms Related to Pernicious Anemia

• Intrinsic Factor

  A glycoprotein secreted by the cells of the gastric glands that is required for the absorption of VITAMIN B 12. Deficiency of intrinsic factor results ...

• Megaloblastic Anemia

  Anemia characterized by the presence of megaloblasts in the bone marrow. (Dorland, 27th ed)

• Tropical Sprue

  A malabsorption syndrome occurring in the tropics and subtropics. Protein malnutrition is usually precipitated by the malabsorption, and anemia due to folic acid deficiency is ...

• Vitamin B12 Deficiency

  A nutritional condition produced by a deficiency of VITAMIN B 12 in the diet, characterized by megaloblastic anemia. Since vitamin B 12 is not present ...

• Vitamin B6 Deficiency

  A nutritional condition produced by a deficiency of VITAMIN B 6 in the diet, characterized by dermatitis, glossitis, cheilosis, and stomatitis. Marked deficiency causes irritability, ...

• Hypoplastic Anemia

  A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements.

• Vitamin M

  A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, ...

• Gastric Parietal Cell

  Cells of the gastric glands which secrete hydrochloric acid and intrinsic factor.

• Folic Acid Deficiency

  A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy ...

• Dyserythropoietic, Congenital Anemia

  A familial disorder characterized by anemia with multinuclear erythroblasts, karyorrhexis, asynchrony of nuclear and cytoplasmic maturation, and various nuclear abnormalities of bone marrow erythrocyte precursors. ...