PI-3 Kinase Definition in Medical Conditions Dictionary

PI-3 Kinase:

An enzyme that catalyzes the conversion of phosphatidylinositol to phosphatidylinositol 3-phosphate. This is the first committed step in the biosynthesis of phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. This pathway is thought to play a critical role in DNA repair, V(D)J recombination and cell cycle checkpoints. EC 2.7.1.137.

Terms Related to PI-3 Kinase

Map Kinase Kinase
A serine-threonine protein kinase family whose members are components in protein kinase cascades activated by diverse stimuli. These MAPK kinases phosphorylate MITOGEN-ACTIVATED PROTEIN KINASES and ...
MAP Kinase Kinase Kinase
Mitogen-activated protein kinase kinase kinases (MAPKKKs) are serine-threonine protein kinases that initiate protein kinase signaling cascades. They phosphorylate MITOGEN-ACTIVATED PROTEIN KINASE KINASES; (MAPKKs) which in ...
MAP ERK Kinase
A serine-threonine protein kinase family whose members are components in protein kinase cascades activated by diverse stimuli. These MAPK kinases phosphorylate MITOGEN-ACTIVATED PROTEIN KINASES and ...
MAP Kinase Module
An intracellular signaling system involving the MAP kinase cascades (three-membered protein kinase cascades). Various upstream activators, which act in response to extracellular stimuli, trigger the ...

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Medical Conditions Dictionary

PI-3 Kinase Definition

Terms Related to PI-3 Kinase

Map Kinase Kinase

MAP Kinase Kinase Kinase

MAP ERK Kinase

MAP Kinase Module

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