Terms Related to Second-Site Suppressor Gene

• Genetic Suppression

  The restoration of the wild-type phenotype in an organism possessing a mutationally altered genotype. The effects of the mutation may be suppressed by a second ...

• Onco-Suppressor Gene

  Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or ...

• nf 2 Gene

  Tumor suppressor genes located on the long arm of human chromosome 22. Mutation or loss of these genes causes NEUROFIBROMATOSIS 2.

• Multiple Tumor Suppressor 1

  A gene product of the p16 tumor suppressor gene (GENES, P16). It is also called INK4 or INK4A because it is the prototype member the ...

• nf 1 Gene

  Tumor suppressor genes located on the long arm of human chromosome 17 in the region 17q11.2. Mutation of these genes is thought to cause NEUROFIBROMATOSIS ...

• nf 2 Genes

  Tumor suppressor genes located on the long arm of human chromosome 22. Mutation or loss of these genes causes NEUROFIBROMATOSIS 2.

• BRCA1 Gene

  A tumor suppressor gene (GENES, SUPPRESSOR, TUMOR) located on human chromosome 17 at locus 17q21. Mutations of this gene are associated with the formation of ...