Steroid 11-Hydroxylase Definition

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Steroid 11-Hydroxylase:

A steroid hydroxylase system found in adrenal tissues. It catalyzes the 11-hydroxylation of steroids in the presence of molecular oxygen and consists of an NADPH-specific flavoprotein, a non-heme iron protein, and cytochrome P-450. Its deficiency is a cause of congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL). EC 1.14.15.4.


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