Tauopathy Definition in Medical Conditions Dictionary

Tauopathy:

Neurodegenerative disorders involving deposition of abnormal tau protein isoforms (TAU PROTEINS) in neurons and glial cells in the brain. Pathological aggregations of tau proteins are associated with mutation of the tau gene on chromosome 17 in patients with ALZHEIMER DISEASE, DEMENTIA, PARKINSONIAN DISORDERS, progressive supranuclear palsy (SUPRANUCLEAR PALSY, PROGRESSIVE), and corticobasal degeneration.

Terms Related to Tauopathy

Progressive Supranuclear Palsy
A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is ...
tau Protein
Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into ...
Motor System Disease
Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major ...

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Medical Conditions Dictionary

Tauopathy Definition

Terms Related to Tauopathy

Progressive Supranuclear Palsy

tau Protein

Motor System Disease

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