Inclusion Body, Sporadic Myositis Definition


Inclusion Body, Sporadic Myositis: Progressive myopathies characterized by the presence of inclusion bodies on muscle biopsy. Sporadic and hereditary forms have been described. The sporadic form is an acquired, adult-onset inflammatory vacuolar myopathy affecting proximal and distal muscles. Familial forms usually begin in childhood and lack inflammatory changes. Both forms feature intracytoplasmic and intranuclear inclusions in muscle tissue. (Adams et al., Principles of Neurology, 6th ed, pp1409-10)

Synonym: sporadic inclusion body myositis, sporadic inclusion body myopathy, inclusion body myositis, inclusion body myositides, inclusion body, sporadic myopathy.

Additional tags: sporadic myositis