Acoustic, Bilateral Schwannoma Definition


Acoustic, Bilateral Schwannoma: An autosomal dominant disorder characterized by a high incidence of bilateral acoustic neuromas as well as schwannomas (NEURILEMMOMA) of other cranial and peripheral nerves, and other benign intracranial tumors including meningiomas, ependymomas, spinal neurofibromas, and gliomas. The disease has been linked to mutations of the NF2 gene (GENES, NEUROFIBROMATOSIS 2) on chromosome 22 (22q12) and usually presents clinically in the first or second decade of life.

Synonym: familial acoustic neuroma, bilateral acoustic neurofibromatosis, type ii neurofibromatosis, neurofibromatosis type ii, neurofibromatosis ii, central nf2 neurofibromatosis, type 2 neurofibromatosis, neurofibromatosis type 2s, neurofibromatosis type 2, neurofibromatosis 2, acoustic, bilateral neuroma, acoustic, bilateral neurofibromatosis.