Deletion of Short Arm of Chromosome 5 Syndrome Definition


Deletion of Short Arm of Chromosome 5 Syndrome: An infantile syndrome characterized by a cat-like cry, failure to thrive, microcephaly, MENTAL RETARDATION, spastic quadriparesis, micro- and retrognathia, glossoptosis, bilateral epicanthus, hypertelorism, and tiny external genitalia. It is caused by a deletion of the short arm of chromosome 5 (5p-).

Synonym: crying cat syndrome, cri du chat syndrome, chromosome 5p syndrome, chromosome 5 short arm deletion syndrome, 5p deletion syndrome, 5p- syndrome.