GABA(A) Receptor Definition
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GABA(A) Receptor: Cell surface proteins which bind GAMMA-AMINOBUTYRIC ACID and control an integral membrane chloride channel. GABA-A receptors are the most prevalent inhibitory neurotransmitter receptors in the brain. Several isoforms have been cloned, and they belong to a superfamily which includes nicotinic receptors, glycine receptors, and 5HT-3 receptors. Most GABA-A receptors have separate modulatory sites sensitive to benzodiazepines and to barbiturates.
Synonym: gaba benzodiazepine receptor, diazepam receptor, benzodiazepine receptor, benzodiazepine gaba receptor, muscimol receptor, gaba-a receptor.