Gene Transfer Technique: The introduction of functional (usually cloned) genes into cells and organisms. A variety of techniques can be used for gene transfer: (1) cell hybridization; (2) microcell-mediated gene transfer; (3) chromosome-mediated gene transfer; (4) DNA-mediated gene transfer. Gene transfer results in genetically transformed cells and individuals and is a step in recombinant DNA technology when cloned genes are being used for transfer. (Rieger, et al., Glossary of Genetics: Classical and Molecular, 5th ed)

Terms Related to Gene Transfer Technique:

• Recombinant Transgene

  Genes that are introduced into an organism using GENE TRANSFER TECHNIQUES.

• Gene Cluster

  A set of genes descended by duplication and variation from some ancestral gene. Such genes may be clustered together on the same chromosome or dispersed ...

• Gene Therapy

  The introduction of new genes into cells for the purpose of treating disease by restoring or adding gene expression. Techniques include insertion of retroviral vectors, ...

• Passive Antibody Transfer

  Transfer of immunity from immunized to non-immune host by administration of serum antibodies, or transplantation of lymphocytes (ADOPTIVE TRANSFER).

• Genetic Transduction

  The transfer of bacterial DNA by phages from an infected bacterium in which the DNA originates to another bacterium. This also refers to the transfer ...

• Liposome

  Artificial, single or multilaminar vesicles (made from lecithins or other lipids) that are used for the delivery of a variety of biological molecules or molecular ...

• Duplicate Gene

  Two identical genes showing the same phenotypic action but localized in different regions of a chromosome or on different chromosomes. (From Rieger et al., Glossary ...

• Patient Transfer

  Interfacility or intrahospital transfer of patients. Intrahospital transfer is usually to obtain a specific kind of care and interfacility transfer is usually for economic reasons ...

• Passive Transfer of Immunity

  Transfer of immunity from immunized to non-immune host by administration of serum antibodies, or transplantation of lymphocytes (ADOPTIVE TRANSFER).

• TcR Gene

  DNA sequences, in cells of the T-lymphocyte lineage, that code for T-cell receptors. The TcR genes are formed by somatic rearrangement (see GENE REARRANGEMENT, T-LYMPHOCYTE ...