Levomethorphan Definition


Levomethorphan: The d-isomer of the codeine analog of LEVORPHANOL. Dextromethorphan shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is a NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is used widely as an antitussive agent, and is also used to study the involvement of glutamate receptors in neurotoxicity.

Synonym: monohydrate dextromethorphan hydrobromide, dextromethorphan hydrochloride, dextromethorphan hydrobromide, dextromethorphan, delsym, (+-)-isomer dextromethorphan hydrobromide, (+-)-isomer dextromethorphan, racemethorphan.