M1-Type Pyruvate Kinase Definition

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M1-Type Pyruvate Kinase: ATP:pyruvate 2-O-phosphotransferase. A phosphotransferase that catalyzes reversibly the phosphorylation of pyruvate to phosphoenolpyruvate in the presence of ATP. It has four isozymes (L, R, M1, and M2). Deficiency of the enzyme results in hemolytic anemia. EC 2.7.1.40.

Synonym: r-type pyruvate kinase, pyruvate kinase l, pyruvate kinase, m-type pyruvate kinase, m2-type pyruvate kinase, l-type pyruvate kinase.

Additional tags: M1 pyruvate kinase