Acute Necrotizing Encephalitis Definition
Acute Necrotizing Encephalitis: A fulminant and often fatal demyelinating disease of the brain which primarily affects young adults and children. Clinical features include the rapid onset of weakness, SEIZURES, and COMA. It may follow a viral illness or MYCOPLASMA PNEUMONIAE infections but in most instances there is no precipitating event. Pathologic examination reveals marked perivascular demyelination and necrosis of white matter with microhemorrhages. (Adams et al., Principles of Neurology, 6th ed, pp924-5)
Synonym: acute necrotizing encephalitides, acute hemorrhagic leukoencephalitis, acute hemorrhagic leukoencephalitides, subacute hemorrhagic leukoencephalitis, subacute hemorrhagic leukoencephalitides, necrotizing hemorrhagic encephalomyelitis, necrotizing hemorrhagic encephalomyelitides, leukoencephalitis acuta hemorrhagica, hursts disease, hurst syndrome, hurst disease, hemorrhagic necrotizing encephalomyelitis, hemorrhagic necrotizing encephalomyelitides, acute necrotizing hemorrhagic encephalomyelitis.
Additional tags: acute necrotizing encephalitis medical definition