Terms Related to Maximum Tolerated Dose

• Maximum Allowable Concentration

  The maximum exposure to a biologically active physical or chemical agent that is allowed during an 8-hour period (a workday) in a population of workers, ...

• Lethal Dose 50

  The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.

• Drug Tolerance

  Progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued administration. It should be differentiated ...

• Immunologic Dose Response Relationship

  A specific immune response elicited by a specific dose of an immunologically active substance or cell in an organism, tissue, or cell.

• LD50

  The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.

• SENCAR Mouse

  Mice selectively bred for hypersusceptibility to two-stage chemical skin carcinogenesis. They are also hypersusceptible to UV radiation tumorigenesis with single high-dose, but not chronic low-dose, ...

• Radiotherapy Dose Fractionation

  Adminstration of the total dose of radiation (RADIATION DOSAGE) in parts, at timed intervals.