NOD Mouse Definition


NOD Mouse: A strain of non-obese diabetic mice developed in Japan that has been widely studied as a model for T-cell-dependent autoimmune insulin-dependent diabetes mellitus in which insulitis is a major histopathologic feature, and in which genetic susceptibility is strongly MHC-linked.

Synonym: non-obese diabetic mouse, non-obese diabetic mice, nod mice, inbred nod mouse, inbred nod mice.

Additional tags: NOD mouse substrains